Robert
Nowinski – Publications in
Biochemistry
1. Rubin, C.S., Dancis, J., Yip, L., Nowinski,
Robert, and Balis, M.E. Purification of IMP: Pyrophosphate
phosphoribosyltransferase catalytically incompetent enzymes in
Lesch-Nyhan disease. Proc. Natl. Acad. Sci. 678:1461-1464, 1971.
2. Ledbetter, J., Nowinski, Robert, and Eisenman,
R. Biosynthesis and metabolism of viral proteins expressed on the
surface of murine leukemia virus-infected cells. Virology
91:116-129, 1978.
3. Pollack, S.B., Tam, M.R., Nowinski, Robert, and
Emmons, S.L. Presence of T cell-associated surface antigens on
murine NK cells. J. Immunology 123:1818-1821, 1979.
4. Young, W.W., Jr., MacDonald, E.M.S., Nowinski,
Robert, and Hakomori, S. Production of monoclonal antibodies
specific for two distinct steric portions of the glycolipid
ganglio-N-triosylceramide (Asialo GM2). J. Exp. Med.
150:1008-1019, 1979.
5. Siadak, A.W. and Nowinski, Robert.
Identification of Ly-5 and T200 antigens on identical cell surface
proteins. J. Immunology 125:1400-1401, 1980.
6. Nowinski, Robert, Berglund, C., Lane, J., Lostrom,
M., Bernstein, I., Young, W., and Hakomori, S. Human monoclonal
antibody against Forssman antigen. Science 210:537-539, 1980.
7. Nudelman, E., Hakomori, S., Knowles, B.B., Solter,
D., Nowinski, Robert, Tam, M.R., and Young, W.W., Jr. Monoclonal
antibody directed to the stage-specific embryonic antigen (SSEA-1)
reacts with a branched glycosphingolipid similar in structure to Ii
antigen. Biochemistry and Biophysical Research Communications
97:443-451, 1980.
8. Kamoun, M., Martin, P.J., Hansen, J.A., Brown,
M.A., Siadak, A.W., and Nowinski, Robert. Identification of a
human T lymphocyte surface protein associated with the E-rosette
receptor. J. Exp. Med. 153:207-212, 1981.
9. Lane, J., Brown, M., Bernstein, I., Wilcox, P.I.,
Slichter, S.J., and Nowinski, Robert. Serological and biochemical
analysis of the P1A1 alloantigen of human platelets. British
Journal of Haematology 50:351-361, 1982.
Robert Nowinski – Publications in Cancer Research
1. Chang, S., Nowinski, Robert, Nishioka, K., and
Irie, R.F. Immunological studies on mouse mammary tumors.
IV. Further characterization of a mammary tumor antigen and its
distribution in lymphatic cells of allogeneic mice. Int. J.
Cancer 9:409-416, 1972.
2. Varmus, H.E., Quintrell, N.N., Medeiros, E.,
Bishop, J.M., Nowinski, Robert, and Sarkar, N.H. Transcription of
mouse mammary tumor virus genes in tissues from high and low tumor
incidence mouse strains. J. Mol. Biol. 79:663-679, 1973.
3. Nowinski, Robert and Peters, E.D. Cell
surface antigens associated with murine leukemia virus:
Definition of the GL and GT antigenic systems. J. Virology
12:1104-1117, 1973.
4. Nowinski, Robert and Kaehler, S.L. Antibody
to leukemia virus: Widespread occurrence in inbred mice.
Science 185:869-871, 1974.
5. Nowinski, Robert, Kaehler, S.L., and Burgess,
R.R. Immune response of the mouse to endogenous leukemia
viruses. Cold Spring Harbor Symposium XXXIX, 1123-1128, 1975.
6. Rapp, U.R., Nowinski, Robert, Reznikoff, K., and
Heidelberger, C. The role of endogenous oncornaviruses in
chemically-induced transformation. I. Transformation independent
of virus production. Virology 65:392-409, 1975.
7. Zarling, J.M., Nowinski, Robert, and Bach,
F.H. Lysis of leukemia cells by spleen cells of normal
mice. Proc. Natl. Acad. Sci. 72:2780-2784, 1975.
8. Nowinski, Robert and Klein, P.A. Anomalous
reactions of mouse alloantisera with cultured tumor cells.
II.Cytotoxicity caused by antibodies to leukemia viruses. J.
Immunol. 115:1261-1268, 1975.
9. Nowinski, R.C. Immune response to leukemia
viruses in mice. In, Viral Immunology and Immunopathology,
Notkins, A., Ed., Academic Press, New York, pp. 237-260, 1975.
10. Nowinski, Robert, Kaehler, S.L., and Baron,
J. Genetic control of natural immunity to ecotropic mouse
leukemia viruses. I. Production of endogenous immunogen.
Infection and Immunity 13:1091-1097, 1976.
11. Nowinski, Robert Genetic control of natural
immunity to ecotropic mouse leukemia viruses. II. Immune
response genes. Infection and Immunity 13:1098-1102, 1976.
12. Wettstein, P.J., Krammer, R., Nowinski, Robert,
David, C.S., Frelinger, J.A., and Schreffler, D.C. A cautionary
note regarding Ia and H-2 typing of murine lymphoid tumors.
Immunogenetics 3:507-516, 1976.
13. Nowinski, Robert and Doyle, T. Antibody to
murine leukemia virus: Genetic control by the Ir-1 locus in PL
mice. J. Immunology 117:350-351, 1976.
14. Nowinski, Robert and Miller, E.C.
Endogenous oncornaviruses in chemically-induced transformation.
II. Effect of virus production in vivo. J. Natl. Cancer Inst.
57:1347-1350, 1976.
15. Nowinski, Robert and Doyle, T. Cellular
changes in the thymuses of preleukemic AKR mice: Correlation with
changes in the expression of murine leukemia viruses. Cell
12:341-353, 1977.
16. Brown, J.P., Klitzman, J.M., Hellstrom, I.,
Nowinski, Robert, and Hellstrom, K.E. Antibody response of mice
to chemically induced tumors. Proc. Natl. Acad. Sci. 75:955-958,
1978.
17. Nowinski, Robert and Hays, E.F.
Oncogenicity of AKR endogenous leukemia viruses, J. Virology 27:13-18,
1978.
18. Ledbetter, J., Nowinski, Robert, and Eisenman,
R. Biosynthesis and metabolism of viral proteins expressed on the
surface of murine leukemia virus-infected cells. Virology
91:116-129, 1978.
19. Nowinski, Robert, Brown, M., Doyle, T., and
Prentice, R. Genetic and viral factors influencing the
development of spontaneous leukemia in AKR mice. Virology
96:186-204, 1979.
20. Green, W.R., Nowinski, Robert, and Henney,
C.S. The generation and specificity of cytotoxic T cells raised
against syngeneic tumor cells bearing AKR/Gross murine leukemia virus
antigens. J. Exp. Med. 150:51-66, 1979.
21. Brown, J., Boiocchi, M., and Nowinski,
Robert Detection of polymorphism in BALB/c leukemia viruses with
mouse antisera. J. Virology 32:345-349, 1979.
22. Pollack, S.B., Tam, M.R., Nowinski, Robert, and
Emmons, S.L. Presence of T cell-associated surface antigens on
murine NK cells. J. Immunology 123:1818-1821, 1979.
23. Young, W.W., Jr., MacDonald, E.M.S., Nowinski,
Robert, and Hakomori, S. Production of monoclonal antibodies
specific for two distinct steric portions of the glycolipid
ganglio-N-triosylceramide (Asialo GM2). J. Exp. Med.
150:1008-1019, 1979.
24. Bernstein, I.D., Tam, M.R., and Nowinski,
Robert Mouse leukemia: Therapy with monoclonal antibodies
against a thymus differentiation antigen. Science 207:68-71, 1980.
25. Bernstein, I.D., Nowinski, Robert, Tam, M.R.,
McMaster, B., Houston, L.L., and Clark, E.A. Monoclonal Antibody
Therapy of Mouse Leukemia, In, Monoclonal Antibodies, Kennett, R.H.,
McKearn, T.J., and Bechtol, K.B., eds., Plenum Press, pp. 275-291, 1980.
26. Hansen, J.A., Martin, P.J., and Nowinski,
Robert. Monoclonal antibodies identifying a novel T cell antigen
and Ia antigens of human lymphocytes. Immunogenetics 10:247-260,
1980.
27. Bernstein, I.D., Nowinski, Robert, and Stiefel,
J. The role of viral and cell-associated antigens in the
cell-mediated immune response of rats to virus-induced lymphoma
cells. J. Immunology 124:1727-1732, 1980.
28. Green, W.R., Nowinski, Robert, and Henney,
C.S. Specificity of cytolytic T cells directed against AKR/Gross
virus-induced syngeneic leukemias: Antibodies directed against
H-2K, but not against viral proteins, inhibit lysis. J.
Immunology 125:647-655, 1980.
29. Houston, L.L., Nowinski, Robert, and Bernstein,
I.D. Specific in vivo localization of monoclonal antibodies
directed against the Thy 1.1 antigen. J. Immunology 125:837-843,
1980.
30. Siadak, A.W. and Nowinski, Robert.
Identification of Ly-5 and T200 antigens on identical cell surface
proteins. J. Immunology 125:1400-1401, 1980.
31. Martin, P.J., Hansen, J.A., Nowinski, Robert, and
Brown, M.A. A new human T cell differentiation antigen:
Unexpected expression on chronic lymphocytic leukemia cells.
Immunogenetics 11:429-439, 1980.
32. Nudelman, E., Hakomori, S., Knowles, B.B.,
Solter, D., Nowinski, Robert, Tam, M.R., and Young, W.W., Jr.
Monoclonal antibody directed to the stage-specific embryonic antigen
(SSEA-1) reacts with a branched glycosphingolipid similar in structure
to Ii antigen. Biochemistry and Biophysical Research
Communications 97:443-451, 1980.
33. Hansen, J.A., Martin, P.J., Kamoun, M.,
Torok-Storb, B., Newman, W., Nowinski, Robert, and Thomas, E.D.
Monoclonal antibodies recognizing human T cells: Potential role
for preventing graft-versus-host reactions following allogeneic marrow
transplantation. Transplantation Proceedings 13:1133-1137, 1981.
34. Siadak, A.W. and Nowinski, Robert.
Thy-2: A murine thymocyte-brain alloantigen controlled by a
gene linked to the major histocompatibility complex.
Immunogenetics 12:45-58, 1981.
35. Martin, P.J., Hansen, J.A., Siadak, A.W., and
Nowinski, Robert. Monoclonal antibodies recognizing normal human
T lymphocytes and malignant human B lymphocytes: A comparative
study. J. Immunology 127:1920-1923, 1981.
36. Houston, L.L. and Nowinski, Robert.
Cell-specific cytotoxicity expressed by a conjugate of ricin and murine
monoclonal antibody directed against thy 1.1 antigen. Cancer
Research, 41:3913-3917, 1981.
37. Bernstein, I.D., Nowinski, Robert, and Wright,
P.W. Monoclonal Antibodies: Prospects for Cancer Treatment,
In, Immunological Approaches to Cancer Therapeutics, Mihich, E., ed.,
John Wiley and Sons, Inc., New York, pp. 277-297, 1982.
38. Bernstein, I.D. and Nowinski, Robert.
Monoclonal Antibody Treatment of Transplanted and Spontaneous Murine
Leukemia, In, Hybridomas in the Diagnosis and Treatment of Cancer,
Mitchell, M. and Oettgen, H.F., eds., Raven Press, New York, pp.
97-112, 1982.
39. Tam, M.R., Bernstein, I.D., and Nowinski,
Robert. Alteration of lymphoid cells in AKR mice by treatment
with monoclonal antibody against Thy 1 antigen. Transplantation
33:269-273, 1982.
40. Pedersen, F.S., Crowther, R.L., Hays, E.F.,
Nowinski, Robert, and Haseltine, W.A. Structure of retroviral
RNAs produced by cell lines derived from spontaneous lymphomas of AKR
mice. J. Virology 41:18-29, 1982.
41. O'Donnell, P.V., Nowinski, Robert, and Stockert,
E. Amplified expression of murine leukemia virus (MuLV)-coded
antigens or thymocytes and leukemia cells of AKR mice after infection
by dualtropic (MCF) MuLV. Virology 119:450-464, 1982.
Robert Nowinski – Publications in Diagnostics
1. Robert Nowinski and Allan Hoffman. Polymerizable
Compounds & Methods for Preparing Synthetic Polymers that
Integrally Contain Polypeptides, No. 4,511,478, issued 4/16/85.
2. Robert Nowinski and Allan Hoffman. Synthesis of
Polymers Containing Integral Antibodies, No. 4,609,707, issued 9/2/86.
3. Auditore-Hargreaves, K., Houghton, R.L., Monji,
N., Priest, J.H., Hoffman, A.S., and Nowinski, Robert. Phase
separation immunoassays. Clin. Chem. 33:1509-1516, 1987.
4. Robert Nowinski and Allan Hoffman.
Polymerization-Induced Separation Immunoassays, No. 4,711,840, issued
12/8/87.
5. Elaine Thomas, Dennis Schwartz, John Priest,
Robert Nowinski, and Allan Hoffman. Polymerization-Induced Separation
Assays Employing Recognition Pairs, No. 4,749,647, issued 6/7/88.
6. Robert Nowinski, Allan Hoffman, Raymond Houghton,
John Priest, and Nobuo Monji. Synthesis of Polymers Containing Integral
Antibodies, No. 4,752,638, issued 6/21/88.
7. Robert Nowinski and Allan Hoffman.
Polymerization-Induced Separation Immunoassays, No. 4,834,010, issued
6/27/89.
8. Monji, N., Cole, C.A., Tam, M., Goldstein, L., and
Nowinski, Robert. Application of a thermally-reversible
polymer-antibody conjugate in a novel membrana-based immunoassay.
Biochemical $ Biophysical Research Communications. 172: 652-660, 1990.
9. Robert Nowinski. Method of Enhancing Direct
Immunofluorescence Staining of Cells, No. 5,068,178, issued 11/26/91.
10. Robert Nowinski and Allan Hoffman.
Polymerizable Compounds Integrally Containing Antibodies and their Uses
in Polymerization Induced Separation Immunoassays, No. EP 0142810 B1,
issued 2/16/94.
11. Robert Nowinski, Luc Montagnier, and David
Klatzmann. Methods for Utilizing Cell Lines which Lack Human
Class II Histocompatibility Antigens, No. EP 0220970 B1, issued 1/10/96.
12. Hoffman, A.s., Stayton, P.S., Bulmus, V., Chen
G., Shoemaker, S., Yang, H.J., Monji, N., Nowinski, Robert, Cole, C.A.,
Priest, J.H., Harris, J.M., Nakamae, K., Nishino, T., and Miyata,
T. Founder’s Award, Society for Biomaterials. Really smart
bioconjugates of smart polymers and receptor proteins. J. Biomed.
Materials Research 52:577-586, 2000.